Prinsexx -> RE: BDSM-a natural approach to longetivity? (7/8/2008 5:12:29 AM)
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ORIGINAL: mike285 Oh no..I'm not propounding a theory...LOL...just a whimsical hypothesis. I'll leave it to a budding researcher to decide if it is capable of being formulated into a theory. He/She will have great fun researching and testing !! on skin and endorphin reception......rub it in me baby.......... (any other research go to scirus.com) J Cosmet Dermatol. 2003 Jul;2(3-4):195-8.Related Articles, Links The 'beauty' of skin neurobiology. Pincelli C, Bonté F. Department of Internal Medicine, Section of Dermatology, University of Modena and Reggio Emilia, Modena, Italy. [email protected] The skin is the most densely innervated organ in the body and there is a close relationship between the skin and the nervous system. Most skin cells express receptors for neuromediators (NM) and skin cells themselves are an important source of NM. In particular, human keratinocytes synthesize neurotrophins and endorphins and express their receptors. In addition to neurotrophic activity, NM are involved in skin homeostasis, trophism and stress responses. NM released from keratinocytes also function in a paracrine fashion on other skin cells, such as Langerhans cells, melanocytes and fibroblasts. We discuss the influence of NM on these cells, which may be involved in major cosmetic problems like ageing, baldness and dyspigmentation. Based on this correlation, it seems reasonable to target neural factors for cosmetic purposes.
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