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ORIGINAL: Milesnmiles

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ORIGINAL: DomKen
No scientist who knows what he is talking about would say that.

If you say so.

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The processes involved, transcription and translation mainly, really do not care about chromosomes at all. We just find it convenient to look at the genetic material at a very specific point in the life cycle of the cell and at that point the DNA is in discrete chromosomes. The rest of the time, not so much.

Let's look at this. Perhaps you can explain why this genetic material, which doesn't seem to care about the number chromosomes, seems to care when it forms chromosomes. In reality, we don't find specific living cells randomly creating random numbers of chromosomes, they seem to make the same number over and over again.

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It literally made no difference when the first hominid with chromosome 2a and 2b fused into chromosome 2 mated with his/her unmutated mate all the genes still matched up.

Again when we look around us, it seems to make a difference, as was pointed out when looking at mules, it generally causes infertility and when it doesn't there isn't a new sustained species developed with a different number of chromosomes, the number seems to always go back to one number or the other.
;-)