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abytchgoddess4u -> RE: .mmr 'scare' doctor to face charges. (7/19/2007 8:20:42 PM)
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You wanted reputable evidence?
I'll give you some...but with a slightly different twist. I don't believe vaccines 'cause' autism, but I do believe that mercury toxicity mimics autism and many children are misdiagnosed as autistic when they are toxic. I also think that exposure often begins in pregnancy and not all cases should be attributed to vaccine exposure.
Here is a link to a retrospective study discussing the downward trend of autism rates since Thimerosal was removed from vaccines...published in the Journal of American Physicians and Surgeons, Volume11, Number1, Spring06.
http://www.jpands.org/vol11no1/geier.pdf
There is a criticism of the article and a response from the authors published in the next issue of the magazine, which may clarify any questions you may have. http://www.jpands.org/vol11no2/correspondence.pdf
Secondly, a reference from Emedicine discussing the causes and symptoms of mercury toxicity/poisoning.
http://www.emedicine.com/EMERG/topic813.htm
It discusses all types, but I ask you to look at the organic types specifically, as Thimerosal is an organomercury. Organomercury compounds are the methylmercury cation, CH3Hg+; ethylmercury cation, C2H5Hg+; dimethylmercury, (CH3)2Hg, and Merbromin ("Mercurichrome").
These quotes will be of most relevance...
"Alkyl organic mercury has high lipid solubility and is distributed uniformly throughout the body, accumulating in the brain, kidney, liver, hair, and skin. Organic mercurials also cross the blood brain barrier and placenta and penetrate erythrocytes, attributing to neurological symptoms, teratogenic effects, and high blood to plasma ratio, respectively."
"Methylmercury has a high affinity for sulfhydryl groups, which attributes to its effect on enzyme dysfunction. One enzyme that is inhibited is choline acetyl transferase, which is involved in the final step of acetylcholine production. This inhibition may lead to acetylcholine deficiency, contributing to the signs and symptoms of motor dysfunction."(Acetylcholine is important for learning and memory as well.)
"- Organic mercury poisoning usually results from ingestion of contaminated food. The long chain and aryl forms of organic mercury have similar characteristics of inorganic mercury toxicity.
- The onset of symptoms usually is delayed (days to weeks) after exposure.
- Organic mercury targets enzymes, and the depletion of these enzymes must occur before the onset of symptoms.
- Symptoms related to toxicity are typically neurological, such as visual disturbance (eg, scotomata, visual field constriction), ataxia, paresthesias (early signs), hearing loss, dysarthria, mental deterioration, muscle tremor, movement disorders, and, with severe exposure, paralysis, and death.
- Organic mercury targets specific sites in the brain, including the cerebral cortex (especially visual cortex), motor and sensory centers (precentral and postcentral cortex), auditory center (temporal cortex), and cerebellum.
- All forms of mercury are toxic to the fetus, but methylmercury most readily passes through the placenta. Even with an asymptomatic patient, maternal exposure can lead to spontaneous abortion or retardation."
"- The causes of organic mercury toxicity include antiseptics, bactericidals, embalming agents, the farming industry, fungicides, germicidal agents, insecticidal products, laundry products, diaper products, paper manufacturing, pathology products, histology products, seed preservation, and wood preservatives.
- Another route of organic mercury exposure is thimerosal, an additive preservative used in vaccines to prevent bacterial contamination. The most commonly used vaccines that contain Thimerosal are for diphtheria-tetanus-whole cell pertussis (DTP), Haemophilus influenzae (HIB), and hepatitis B." (Hep B vaccines should no longer have Thimerosal, but I'm not sure about DPT and HIB.)
Funnily enough, seems like the NIH is curious about mercury poisoning and autism too...they're doing a study with regard to treatment of children with autism by chelation.
http://clinicaltrials.gov/show/NCT00376194
As to 'actual' autism increases, I think it's much more related to the use of ultrasound and doppler use in pregnancy.
ETA: The Center for Children’s Health and the Environment (CCHE) of Mount Sinai School of Medicine used the CDC's OWN data on infants' cord blood levels of mercury to show the potential loss of income of those infants...since mercury poisoning has been shown to decrease IQ levels.
http://www.ehponline.org/docs/2005/7743/abstract.html
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