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ORIGINAL: pahunkboy

It takes 5 hours a day to do dialysis? 

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ORIGINAL: pahunkboy

Can kidneys be bad- but the liver is fine?

She had been in a terrible car accident-  5 years ago.

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ORIGINAL: Muttling

I've got a unique question.....



What does her doctor suggest??????

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ORIGINAL: Termyn8or
Now I am not sure, but I am sure someone knows, if you DO go in for dialaysis for five hours you don't have to have it every day. I am not sure how often, but it's not every day. I do believe that certain drugs and diet plans can lessen the needed frequency for it as well, but I have never researched it. Others can say better.

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People have the mistaken idea that kindeys and the liver filter out waste products and poisons. This is not true.

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Dialysis doesn't quite do the jpb. It will remove the toxins, which didn't used to be toxins, but these enzymes are not put back where they need to be for life. This leads to digestive anomalities and therefore malabsorption diseases. It is not pretty.

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ORIGINAL: pahunkboy

This is one of the neighbors...  not the one I have dinner with.  She is around my age 47.   The DR called her boyfriend--  and asked him some blunt questions-  possibly against HIIPA.   He answered truthfully as he wants to help her.  She is in the hospital now.

I dont talk to her much-  but I do like her.   I stay my distance because she IS dating the other neighbor, you understand.

She had a bad accident some time ago... and had been on pain pills.

I guess-  from what I heard-  she was on so many of them- she "barely knows who she is".

Her brother age 42 passed away last month in that same house.  I get along fine with them-  I sent my condolences. 

Anyhow- she DOES have serious injury issues-  but now she also has kidneys  "shutting down", and the DR wont give her anymore of them.

She drinks alot of coffee and soda and smokes so heavily- I gagged on her back porch.

She is a nice lady- and does not deserve this.

I just did not think opiods affected the kidneys.        Oh-   we think that she obtained more pills when her brother passed away----- that had been his.  Which does not make sense to me- because police come and pick up those rxs when someone dies locally.

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ORIGINAL: Termyn8or

"My blood is B+ tell me if I was match.... we will talk about the price "

Offering blood for sale like organs is illegal here. Not that I care, but that's how it is. My shit is O negative which is the most valuable on the planet. Too bad, not for sale at any price. I give it or not. What, I'm gonna drive over to Pennsylvania to give some to someone I don't know ? I don't think so.

But transfusions are worth shit, you would need them almost every day. Now I am not sure, but I am sure someone knows, if you DO go in for dialaysis for five hours you don't have to have it every day. I am not sure how often, but it's not every day. I do believe that certain drugs and diet plans can lessen the needed frequency for it as well, but I have never researched it. Others can say better.

People have the mistaken idea that kindeys and the liver filter out waste products and poisons. This is not true. These are needed substances in the body, they only become toxic when they do not go where they are suposed to go. These are enzymes etc. which are recycled, but they can't remain in the ailimentary tract. They come out into these glands and if processed correctly come back in to again facilitate the digestive process.

Dialysis doesn't quite do the jpb. It will remove the toxins, which didn't used to be toxins, but these enzymes are not put back where they need to be for life. This leads to digestive anomalities and therefore malabsorption diseases. It is not pretty.

And like with cihrrosis(sp) of the liver, that bile belongs in a certain part of the body, around the small intesinte. IT IS toxic when it is in other places, causing jaundice and shit.

These glandular diseases are among the most poorly recognized and treated in this country, and I think in other countries as well. Doctors are great at rebuilding your back, eyes and ears, even a few other things, but the endocrine system is not yet fully understood, and even less so by many doctors, unless they specialise in it. And MONEY caused that.

T^T

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ORIGINAL: pahunkboy

It takes 5 hours a day to do dialysis? 

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ETA : I forgot about uric acid, that's kinda important when it comes to the kidneys, but if you want to say I am totally full of shit, let';s start with your health. Mine is fine. I do what I do based on my opinions. You can listen to people who take your money all day long, doesn't bother me a bit, except I might miss you when you ain't around with whom to argue anymore. But it won't be my fucking fault.

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ORIGINAL: Hippiekinkster

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ORIGINAL: TheShrew
It depends on the med .. they can be filtered then excreted through the kidneys or liver
It's impossible to answer many questions you're going to have without a lot more information.
If her kidneys are crashing, he may have switched her to a med that can be processed through the liver.
If her kidneys are completely shot, then she's looking at dialysis and potentially transplant.
If she's an addict, drying her out isn't the first course of action.. stabilizing her condition is.
If she has other 'serious' injuries, that could be the cause of her kidney failure or at least be a contributing factor.
If not, the other injuries could be a factor in the Drs decision not to pull her meds.
If she's on the edge of gone then the meds are to make her comfortable.
I'm sorry, it's just impossible to give a solid answer.
.. I've never seen this happen ~> police come and pick up those rxs when someone dies locally.

ETA .. to remove medical terms & say I hope your friend gets better.

I don't know of any opioids that are NOT metabo;ized via the liver enzymes (which are also found in the intestinal tract, which is why grapefruit juice (bergamottin) is contraindicated with certain meds). AFAIK, all but codeine and possibly methadone (I'd have to check) are metabolized via the CYP3a4 family of polypeptides. I just had a bout with Rifampin, which, being an inducer of CYP3a4 enzymes, caused me to metabolize my oxy faster than normal, which caused me to "overtake" them, which got me bitched at by my pain doc.

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ORIGINAL: tazzygirl

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ORIGINAL: pahunkboy

It takes 5 hours a day to do dialysis? 

Typically its 4 hours a day, three days a week.  But alot depends on her lab work and physician orders.  In the hospital when I ran patients there on dialysis, it was 2-3 hours a day until discharge.

Your question about why the Dr removed her from her pain meds... could have a few simple answers. 

1) the med could be causing the failure
2) many drugs are dialized out during treatment and hers may have been one of them
3) he may have felt she was too dependent  and needed a holiday.
4) it could also be that the pain meds she was on is excreted by the kidneys, as a result, she would have an overabundance in her system and needed some time off.

Without knowing more or what is exactly causing the pain I cannot say for certain.

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ORIGINAL: TheShrew

I know many of you have considerably more knowledge than I do, and could address the metabolization/meds issue better than I can. {And I'm too lazy to go dig out old books look any of this up.}

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ORIGINAL: Hippiekinkster

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ORIGINAL: TheShrew
It depends on the med .. they can be filtered then excreted through the kidneys or liver
It's impossible to answer many questions you're going to have without a lot more information.
If her kidneys are crashing, he may have switched her to a med that can be processed through the liver.
If her kidneys are completely shot, then she's looking at dialysis and potentially transplant.
If she's an addict, drying her out isn't the first course of action.. stabilizing her condition is.
If she has other 'serious' injuries, that could be the cause of her kidney failure or at least be a contributing factor.
If not, the other injuries could be a factor in the Drs decision not to pull her meds.
If she's on the edge of gone then the meds are to make her comfortable.
I'm sorry, it's just impossible to give a solid answer.
.. I've never seen this happen ~> police come and pick up those rxs when someone dies locally.

ETA .. to remove medical terms & say I hope your friend gets better.

I don't know of any opioids that are NOT metabo;ized via the liver enzymes (which are also found in the intestinal tract, which is why grapefruit juice (bergamottin) is contraindicated with certain meds). AFAIK, all but codeine and possibly methadone (I'd have to check) are metabolized via the CYP3a4 family of polypeptides. I just had a bout with Rifampin, which, being an inducer of CYP3a4 enzymes, caused me to metabolize my oxy faster than normal, which caused me to "overtake" them, which got me bitched at by my pain doc.

ETA ... There are contraindications of certain drugs in relation to specific disease processes. Morphine is the prototype for all opioid drugs, and it's highly contraindicated in pts w/ renal impairment d/t the accumulation of a toxic metabolite. {Though I would have to go look up which metabolite} Demerol is another that holds the potential to induce a toxic state in pts w/ kidney disfunction d/t accumulation. And, as you probably already know, oxycodone is structurally r/t morphine so I assumed it may be avoided for the same reasons. {Although I 'd have to go and look this up, too.} 

When I typed that response I felt it was more clear in it's original incarnation. However, I edited to remove any medical terminology/information that sounded better suited for an exchange  between healthcare workers. My goal in doing so was to avoid causing him any further confusion and additional questions. The gist of my reply was to let him know.. no one could give him a definitive answer based on limited knowledge. That being said, and my addressing you directly, I will say ...

It seemed the concern of the OP was .. kidney failure/ still on pain pills/ why. He gently alluded to a pill addiction, serious injuries, smokes so badly he gagged outside her home, and is suddenly in renal failure. Unfortunately, my mind works like this ~> Renal failure + addiction/methadone-narcan, pain/codeine, cancer/morphine etc. But I don't want to say these things to him, so I crafted the most gentle, yet honest, response I could.

I don't know of any opioids that are NOT metabo;ized via the liver enzymes <~  I tried to convey that "not all" drugs are  metabolized/excreted solely via the kidneys. {Which seemed a concern to him.} I never said "no opioids are metabolized hepatically" because most are. Even then, there are variables such as age, specific disease process, comorbidities, poor metabolizer v. good metabolizer, race etc.

which is why grapefruit juice (bergamottin) is contraindicated with certain meds). <~ True, many benzo's, statin's, antibio's etc

AFAIK, all but codeine <~ When codeine is metabolized it breaks down into morphine and another component I cannot recall off the top of my head, but I'm fairly certain it occurs in the liver. {Either way, it's a danger for her because morphine is an issue in pt's w/ renal issues.} 

possibly methadone (I'd have to check) <~ If I recall correctly, the action of methadone is to bind to tissue of the brain and kidneys, though excretion happens via the liver, so it's actually alright as long as her liver is still good.

are metabolized via the CYP3a4 family of polypeptides. <~ I can only congratulate you on committing this type of information to memory. I'm not going to lie .. I do well to remember the most common meds and associated data, pertinent lab values, protocols etc. that we use/see on a daily basis. Anything above/beyond/outside the norm we look up on a client to client basis.

I just had a bout with Rifampin  <~ Sorry to hear you that, but I hope you've recovered/are recovering well.


ETA .. look up there ^ 

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ORIGINAL: Termyn8or

Dude, phosphorous is an essential mineral, recognized by the government. I don't want to stick it to you over that contradiction because this is not an adversary situation. But if you don't get enough phosphorous bad shit will happen. This is an adverse reaction of one's body chemistry caused by dialysis.

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ORIGINAL: Termyn8or

"My blood is B+ tell me if I was match.... we will talk about the price "

Offering blood for sale like organs is illegal here. Not that I care,