Hippiekinkster -> RE: Absinthe? (5/3/2008 3:17:27 AM)
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ORIGINAL: SugarMyChurro A Liquor of Legend Makes a Comeback http://www.nytimes.com/2007/12/05/dining/05absi.html?pagewanted=all The question is: how much thujone is in the bottle? On the other hand, many say it doesn't ultimately matter as the wonders of absinthe may be more in the high alchohol content as opposed to any possible hallucinogens. So yeah, grab a cube of sugar, a spoon and go nuts...! Since thujone exhibits either no, or at best very slight, psychoactive elements it's pretty unlikely it ever did cause hallucinations. The amount you'd have to consume to get anything closer to noticable effects would see you long dead from liver failure before you got halfway there. Combine high alcohol levels with a reputation for making you go all "trippy with the fairies" though and it doesn't matter about the thujone, people will quite happily convince themself they're getting something more than just incredibly drunk. "The presumed active ingredient in wormwood's oils, alpha-thujone, has a similar molecular structure to menthol, a-pinene, eucalyptol, camphor and other monoterpenes. Formerly believed to have a THC (cannabinoid) structure-activity relationship and mechanism, a-thujone is now known to modulate only an entirely different receptor site, the GABA (gamma-aminobutyric acid) system. GABA moderates the firing of neural synapses; a-thujone mildly antagonizes such inhibition." I cannot recall exactly, but I don't believe that GABA receptors have anything to do with psychoactivity a la psychedelics. People used to claim they'd "trip" from mezcal, too.
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